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Chemo Brain

Chemo Brain and How to Outsmart it.

“I can’t keep up in conversations” … “I get stuck on words” … “My thinking is slow” … “I keep forgetting what I’m doing” … “I lose my train of thought”. These are only a few of the complaints that you might hear from those experiencing cognitive changes associated with cancer. Often referred to as “chemo brain,” cancer-related cognitive decline or impairment (CRCD/CRCI) is a side-effect associated with a cancer diagnosis, its treatment, or factors related to treatment. CRCD impacts various cognitive domains including attention, language, processing speed, memory, and executive functioning.  Recent research has shown that up to 75% of those diagnosed with cancer have reported cognitive challenges4. These cognitive difficulties can vary in severity and are sometimes not noticed by others, but only by those experiencing the symptoms.

If these cognitive changes are not often obvious and can be “hidden,” then why is CRCD such a big issue? CRCD can impact a person’s ability to complete daily work and home activities and can significantly reduce quality of life. Oftentimes, those with cognitive symptoms related to cancer suffer in silence, whether due to lack of understanding from medical professionals, limited access to services that can help, or even feeling self-conscious of the cognitive changes. It is important to know that these challenges are common and manageable. The severity and impact of CRCD on one’s daily life can be significantly reduced by managing stress, pain, sleep quality, and anxiety/depression, as well as with interventions such as cognitive rehabilitation, behavioral modifications, and mindfulness3, 5.

 

It is often assumed that CRCD symptoms must simply be “put up with,” and though there is no magic pill to stop or prevent these challenges, there are many ways they can be managed. Of course, it is recommended to seek assistance from medical professionals, such as speech-language pathologists, occupational therapists, psychologists, etc.1 who have experience treating CRCD. As well, below are strategies and techniques that can be implemented at home to mitigate these cognitive challenges.

 

Modify the Environment

Some things are out of your control, especially when experiencing health concerns, including CRCD. When this happens, it is helpful to think about what can be controlled in your environment and day-to-day life. 

 

  • Limit Distractions – This not only includes audible distractions, such as background noise (conversations, music, TV, etc.), but also limiting visual distractions. Keeping a living and work space clean and organized helps to prevent external factors from interrupting the task at hand. 

Physical and Cognitive Activity 

Keeping both your brain and body active are ways to manage cognitive changes and build overall brain health.

  • Exercise – Physical activity can reduce fatigue, enhance aspects of mood, improve quality of life, and manage cognitive symptoms.3

  • Try Something New – Take a college course, start a new hobby, or even try to learn a new language. It’s not necessary to be successful, but just the idea of stimulating your mind is helpful  to “stock up” on your brain’s cognitive abilities.

 

Reduce Cognitive Load 

The brain is constantly working during the day to manage our thoughts, decisions, memory, and so on. When experiencing CRCD, the brain must work harder to do even the simplest of tasks. Giving the brain a break and relying on more external ways to manage cognitive changes can help.

  • Take breaksBe aware of your fatigue and times when your mind begins to wander. Use them as signs to take a “brain break.” This can be as short as a 30-60 second break of doing nothing; sometimes that’s all your brain needs to “reset” and feel more refreshed. 

  • Break it downSet small goals to break down your task. Multi-step tasks, even unloading the dishwasher, can be broken into several steps to avoid being overwhelmed or mentally fatigued. 

  • Write it down When in doubt, write it down! This could be a daily journal or log of events/conversations, a list of “to-dos”, or key words written to jog your memory.

  • Slow down Don’t rush through tasks; intentionally slow down and give yourself time.

 

Work Around It

CRCD is unfortunately not something that will go away with the snap of a finger. Using alternative ways to get your point across when experiencing word-finding issues, memory lapses, or difficulty focusing can reduce stress and feelings of inadequacy related to the cognitive difficulties.

  • Self-talk – Talk yourself through tasks to help you keep track of what you are doing. Think of this like an ongoing narrative in your head, or out loud.

  •  Repeat it – Repeat information to yourself, back to others, or ask for repetition of information back to you. This way you can make sure you have heard the information correctly and can more easily encode and process the information. 

  •  Describe it If you are having difficulty thinking of a word, try to describe it. What does it look like? Where do you find it? What is it for? This can help you to come up with the correct word, or at the very least, whoever you are talking with will be able to help you find the word.

  • Pick an alternate word Sometimes it is easier to replace the word you cannot think of with a similar word that means the same or close to the same thing. 

 

The above techniques can help ease the burden that CRCD can put on your life; however, everybody is different, and results may vary for each person. If you continue to struggle with cancer-related cognitive impairments, an individual treatment plan provided from a skilled clinician may be beneficial. Consider discussing this with your medical team and family to determine what is the best approach to help you outsmart CRCD. 

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Emily Hammack

Written by:

Emily Hammack M.S., CCC-SLP, CBIS

ReVital Cancer Rehab

Featured:

2024 Q4 Edition of Brighter.

References

  1. Fernandes, H.A., Richard, N.M. & Edelstein, K. Cognitive rehabilitation for cancer-related cognitive dysfunction: a systematic review. Support Care Cancer 27, 3253–3279 (2019). https://doi.org/10.1007/s00520-019-04866-2

  2. Jean-Pierre P. Management of Cancer-related Cognitive Dysfunction-Conceptualization Challenges and Implications for Clinical Research and Practice. US Oncol. 2010;6:9-12.  

doi: 10.17925/ohr.2010.06.0.9. 

 

  1. Oliver Rick, Alexandra Gerhardt, Georgia Schilling; Cancer-Related Cognitive Dysfunction: A Narrative Review for Clinical Practice. Oncol Res Treat 6 May 2024; 47 (5): 218–222. https://doi.org/10.1159/000538277

  2. Országhová Z, Mego M, Chovanec M. Long-Term Cognitive Dysfunction in Cancer Survivors. Front Mol Biosci. 2021 Dec 14;8:770413. doi: 10.3389/fmolb.2021.770413. 

  3. Pendergrass JC, Targum SD, Harrison JE. Cognitive Impairment Associated with Cancer: A Brief Review. Innov Clin Neurosci. 2018 Feb 1;15(1-2):36-44. 

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